Omeprazole Paste: Treatment and Prevention of Recurrence of Gastric Ulcers in Horses

Omeprazole as a paste formulation at 4.0 mg/kg PO q 24 h is highly effective in healing gastric ulcers in horses, while 2.0 or 4.0 mg/kg PO q 24 h effectively prevents recurrence of gastric ulcers in Thoroughbred horses in race training. Omeprazole paste did not result in any adverse affects in the horses during the 58-d treatment period. Author’s address: College of Veterinary Medicine, The University of Tennessee, P.O. Box 1071, Knoxville, Tennessee, 37901-1071; Bradford Park Veterinary Hospital, 1255 E. Independence, Springfield, Missouri (Sifferman); Rood & Riddle Equine Hospital, 4901 Mt. Horeb, Lexington, Kentucky (Bernard); Peterson, Smith, Matthews, Hahn and Slone Equine Hospital, 4747 S.W. 60th Avenue, Ocala, Florida (Hughes); Merial Limited, 2100 Ronson Road, Iselin, New Jersey (Holste, Daurio, Alva, Cox). r 1999 AAEP.